Scleroderma (Systemic Sclerosis) Care in Collegeville, PA
Scleroderma is an autoimmune disease that tightens the skin and can involve internal organs. Early, coordinated care makes a difference.
What is scleroderma?
Systemic sclerosis, commonly called scleroderma, is an autoimmune disease in which the body produces excess collagen, causing thickening and tightening of the skin and changes in small blood vessels. It can also affect the digestive tract, lungs, heart, and kidneys. It is not contagious, and it varies widely from person to person.
Common symptoms
- Raynaud's phenomenon, often the earliest sign: fingers that turn white or blue in the cold
- Puffy fingers followed by thickened, tight skin on the fingers, hands, or face
- Small red spots on the skin or sores on the fingertips
- Heartburn, reflux, or trouble swallowing
- Shortness of breath or a persistent dry cough
- Fatigue and joint pain
How scleroderma is diagnosed
Evaluation includes your history, a skin and joint examination, and blood tests for ANA and specific antibodies such as anti-centromere, anti-Scl-70, and anti-RNA polymerase III. A nailfold capillary exam, lung function tests, and heart and chest imaging check whether organs are involved, often before symptoms appear.
Treatment
There is no cure, but treatment is tailored to the organs involved. It can include measures and medications for Raynaud's, treatment for reflux, and immune-modulating medications for skin or lung disease. Regular screening and home blood pressure monitoring help detect problems early.
Medically reviewed by Dr. Shady Abdelbaki, MD · Last reviewed October 25, 2026
Frequently asked questions about scleroderma
What is the difference between localized scleroderma and systemic sclerosis?
Localized scleroderma, also called morphea, affects the skin and sometimes the tissue just beneath it, without involving internal organs. Systemic sclerosis, the form described on this page, can involve the skin and internal organs such as the digestive tract, lungs, heart, and kidneys, which is why it needs regular monitoring.
Does Raynaud's phenomenon mean I have scleroderma?
Not usually. Most people with Raynaud's do not have scleroderma, but Raynaud's that begins later in life or comes with other symptoms deserves an evaluation.
Why are regular lung tests part of scleroderma care?
Lung involvement is common and can be silent at first. Regular testing finds it early, when treatment works best.
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